International Journal of Advanced Research in Computer and Communication Engineering

Abstract: The modern healthcare industry faces a "data deluge," characterized by massive, heterogeneous information streams from Electronic Health Records (EHRs), high-throughput multi-omics experiments (genomics, proteomics), and real-time Internet of Things (IoT) monitoring devices. Traditional computational methods are inadequate to manage the scale defined by the Four V's: Volume, Velocity, Variety, and Veracity. This paper proposes the design of a Precision Healthcare Analytics Platform, a scalable Big Data architecture intended to systematically ingest, integrate, process, and analyze this complex data. The architecture leverages Hadoop Distributed File System (HDFS) for massive, fault-tolerant storage and Apache Spark for high-speed, distributed processing and Machine Learning (ML) capabilities. The core objective is to integrate siloed clinical data with biomolecular profiles, facilitating a critical paradigm shift from population-based generalized care to patient-specific personalized medicine. By employing advanced analytics, including Natural Language Processing (NLP) and predictive modeling, the platform aims to enhance clinical decision-making, improve public health surveillance, and substantially reduce operational costs.

Keywords: Big Data, Personalized Medicine, Precision Healthcare, Hadoop, Apache Spark, Multi-Omics, Predictive Analytics, FHIR, Clinical Decision Support (CDS).

Downloads: | DOI: 10.17148/IJARCCE.2025.141015